RNF144A

Across TCGA patient cohorts, RNF144A mutation is significantly associated with the RNA expression of many other genes, with 2,200 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF144A-associated genes across cancer lineages are MIR5089, MED17, and DSG2. Each is linked with RNF144A in more than 2 cancer types. Because this analysis shows association rather than direction, both RNF144A-to-partner and partner-to-RNF144A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5089 grouped by RNF144A-low versus RNF144A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF144A→partner) and Y-score (partner→RNF144A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR5089 →	+0.574	+4.719	<.001	.003	3	3
UCEC	MED17 →	+0.368	+3.480	.007	.002	3	3
UCEC	DSG2 →	+0.769	+2.332	<.001	.003	3	3
UCEC	FBXO7 →	+0.461	+4.042	<.001	<.001	3	3
UCEC	AAGAB →	+0.521	+2.042	<.001	.001	3	3
UCEC	BLOC1S6 →	+0.558	+3.823	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,200 associations by consensus.

MIR5089 by RNF144A expression — BLCA

Explore this box plot interactively →