RNF144A

Across TCGA pan-cancer cohorts, RNF144A RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of RNF144A’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNF144A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNF144A is over-expressed in tumor, although a few such as KIRC and UCEC show the opposite, repressed pattern.

HNSC, THCA, and LIHC are the cancer types where RNF144A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNF144A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+1.030	<.001	12	view →
THCA	Male	III,IV	+1.185	<.001	10	view →
LIHC	Female	II,III,IV	+1.085	<.001	7	view →
KIRC	Male	II,III,IV	−0.799	<.001	7	view →
BLCA	All	III,IV	+0.875	.003	6	view →
CHOL	All	All	+2.432	<.001	5	view →
LUSC	All	II,III,IV	+0.627	<.001	5	view →
LUAD	Male	All	+0.616	.002	5	view →
STAD	All	II,III,IV	+0.539	.016	5	view →
UCEC	All	All	−1.198	<.001	4	view →
COAD	Female	II,III,IV	−0.855	<.001	4	view →
READ	Female	All	−1.872	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

RNF144A–HNSC

Open the HNSC breakdown →