RNF144A

Across TCGA patient cohorts, RNF144A mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF144A-associated genes across cancer lineages are Rictor_pT1135, Caspase-7-cleavedD198, and c-Jun_pS73. Each is linked with RNF144A in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF144A-to-partner and partner-to-RNF144A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rictor_pT1135 grouped by RNF144A-low versus RNF144A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF144A→partner) and Y-score (partner→RNF144A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rictor_pT1135 →	-0.096	-1.700	.027	.044	3	2
UCEC	Caspase-7-cleavedD198 →	+0.730	+2.341	.003	.019	3	2
UCEC	c-Jun_pS73 →	-0.133	-1.700	.049	.044	3	2
UCEC	EGFR_pY1068 →	-0.301	-2.906	.004	.001	3	1
UCEC	A-Raf_pS299 →	-0.148	-1.700	.003	.044	3	1
UCEC	FOXO3a_pS318_S321 →	-0.114	-2.312	.032	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Rictor_pT1135 by RNF144A expression — UCEC

Explore this box plot interactively →