RNF139

Across TCGA patient cohorts, RNF139 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,631 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNF139-associated proteins across cancer lineages are PTK2, TATDN1, and YTHDF3. Each is linked with RNF139 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNF139-to-partner and partner-to-RNF139 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF139 versus PTK2 in LUAD, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF139→partner) and Y-score (partner→RNF139) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PTK2 →	+0.328	+0.404	<.001	<.001	3	5
OV	TATDN1 →	+0.499	+0.685	.003	.002	3	5
LSCC	YTHDF3 →	+0.255	+0.489	<.001	<.001	3	5
LSCC	NDRG1 →	+0.680	+0.372	<.001	.008	3	4
LUAD	SPCS3 →	-0.424	-0.533	<.001	<.001	3	4
OV	STK3 →	+0.371	+0.775	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,631 associations by consensus.

RNF139 vs PTK2 — LUAD

Explore this scatter interactively →