RNF139

Across TCGA patient cohorts, RNF139 protein abundance is significantly associated with the RNA expression of many other genes, with 4,118 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RNF139-associated genes across cancer lineages are EMC2, MAL2, and NDUFB9. Each is linked with RNF139 in more than 2 cancer types. Because this analysis shows association rather than direction, both RNF139-to-partner and partner-to-RNF139 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF139 versus EMC2 in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF139→partner) and Y-score (partner→RNF139) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EMC2 →	+0.813	+0.642	<.001	<.001	3	3
OV	MAL2 →	+1.345	+0.520	.002	<.001	3	3
OV	NDUFB9 →	+0.810	+0.537	<.001	<.001	3	3
OV	NTAQ1 →	+0.617	+0.574	.003	.002	3	3
OV	COMMD5 →	+0.797	+0.633	<.001	<.001	3	3
OV	MRPL13 →	+0.723	+0.478	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,118 associations by consensus.

RNF139 vs EMC2 — OV

Explore this scatter interactively →