RNF139-AS1

Across TCGA pan-cancer cohorts, RNF139-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated RNF139-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNF139-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNF139-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and UCS show a favorable association.

KIRC, BLCA, and LIHC are the cancer types where RNF139-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.459	0.721	<.001	151	view →
BLCA	OS	Tertile	III,IV	0.606	0.385	<.001	88	view →
LIHC	OS	Quartile	II,III,IV	0.483	0.831	.001	56	view →
ESCA	DFS	Quartile	II,III,IV	0.352	0.634	.001	35	view →
UVM	DFS	Quartile	III,IV	0.129	0.826	<.001	34	view →
CESC	DFS	Quartile	III,IV	0.206	0.845	<.001	32	view →
KICH	OS	Tertile	III,IV	0.169	0.913	.004	28	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
ACC	OS	Tertile	All	0.249	0.717	.003	23	view →
UCEC	OS	Median	IV	0.724	0.260	.006	22	view →
LUAD	DFS	Median	IV	0.270	0.807	.003	21	view →
PAAD	DFS	Median	All	0.369	0.172	.004	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

RNF139-AS1–KIRC (OS)

Open the KIRC breakdown →