RNF126

Across TCGA cell cohorts, RNF126 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF126-associated genes across cancer lineages are TMSB4Y, ETNPPL, and FAM205A. Each is linked with RNF126 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF126-to-partner and partner-to-RNF126 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMSB4Y grouped by RNF126-low versus RNF126-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF126→partner) and Y-score (partner→RNF126) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TMSB4Y →	+1.595	+3.556	<.001	.007	3	1
LARGE_INTESTINE	ETNPPL →	+0.198	+3.758	.006	.004	3	1
LARGE_INTESTINE	FAM205A →	+0.019	+3.766	.001	.004	3	1
LARGE_INTESTINE	GSG1L2 →	+0.013	+4.022	<.001	.006	3	1
BLOOD_Leukemia	HRG →	+0.296	+3.440	<.001	.001	3	1
BLOOD_Leukemia	CASQ2 →	+0.053	+4.412	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

TMSB4Y by RNF126 expression — LARGE_INTESTINE

Explore this box plot interactively →