RNF122

Across TCGA patient cohorts, RNF122 mutation is significantly associated with the RNA expression of many other genes, with 183 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF122-associated genes across cancer lineages are ANAPC15P1, LINC00538, and OR7A17. Each is linked with RNF122 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF122-to-partner and partner-to-RNF122 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANAPC15P1 grouped by RNF122-low versus RNF122-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF122→partner) and Y-score (partner→RNF122) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ANAPC15P1 →	+0.231	+3.061	<.001	<.001	3	2
UCEC	LINC00538 →	+0.059	+3.250	.003	<.001	3	1
SKCM	OR7A17 →	+0.050	+4.680	<.001	.007	3	1
SKCM	RN7SKP186 →	+0.168	+4.771	<.001	.006	3	1
SKCM	RNU1-136P →	+0.304	+4.324	.001	.007	3	1
SKCM	RPL23AP17 →	+0.088	+4.470	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 183 associations by consensus.

ANAPC15P1 by RNF122 expression — UCEC

Explore this box plot interactively →