RNF115

Across TCGA pan-cancer cohorts, RNF115 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RNF115 data layer compared with 23 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNF115 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNF115 expression acts as an unfavorable survival marker.

HNSC and LIHC are the cancer types where RNF115 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.187	0.710	.014	24	view →
LIHC	DFS	Median	All	0.105	0.555	.004	9	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RNF115–HNSC (DFS)

Open the HNSC breakdown →