RNF115

Across TCGA patient cohorts, RNF115 protein abundance is significantly associated with the RNA expression of many other genes, with 6,532 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RNF115-associated genes across cancer lineages are POLR3C, GPR89A, and SNX27. Each is linked with RNF115 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNF115-to-partner and partner-to-RNF115 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF115 versus POLR3C in HNSC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF115→partner) and Y-score (partner→RNF115) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	POLR3C →	+0.633	+0.352	.001	<.001	3	5
HNSC	GPR89A →	+0.519	+0.451	<.001	<.001	3	4
HNSC	SNX27 →	+0.597	+0.291	<.001	<.001	3	4
HNSC	TAF1A →	+0.685	+0.303	.001	<.001	3	4
HNSC	RPRD2 →	+0.665	+0.397	<.001	<.001	3	4
UCEC	PDZK1 →	+0.758	+0.289	.007	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,532 associations by consensus.

RNF115 vs POLR3C — HNSC

Explore this scatter interactively →