RNF115

Across TCGA patient cohorts, RNF115 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF115-associated genes across cancer lineages are lymphatic Endothelial cells, MEP, and CD8+ naive T-cells. Each is linked with RNF115 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF115-to-partner and partner-to-RNF115 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, lymphatic Endothelial cells grouped by RNF115-low versus RNF115-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF115→partner) and Y-score (partner→RNF115) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	lymphatic Endothelial cells →	-0.026	-3.129	.036	.019	3	1
UCEC	MEP →	+0.053	+2.180	<.001	.036	3	1
UCEC	CD8+ naive T-cells →	+0.036	+2.212	.010	.034	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

lymphatic Endothelial cells by RNF115 expression — UCEC

Explore this box plot interactively →