RNF115

Across TCGA cell cohorts, RNF115 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,536 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RNF115-associated GO terms across cancer lineages are Cytosolic transport, Endosome to lysosome transport, and Positive regulation of TORC2 signaling. Each is linked with RNF115 in more than 12 cancer types. Because this analysis shows association rather than direction, both RNF115-to-partner and partner-to-RNF115 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by RNF115-low versus RNF115-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF115→partner) and Y-score (partner→RNF115) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Cytosolic transport →	+0.066	+0.852	<.001	<.001	3	13
OVARY	Endosome to lysosome transport →	+0.072	+0.786	<.001	<.001	3	13
OVARY	Positive regulation of TORC2 signaling →	+0.099	+0.690	<.001	.003	3	13
BONE	Endosomal transport →	+0.062	+0.876	.001	<.001	3	12
OVARY	Golgi vesicle transport →	+0.051	+0.661	.001	<.001	3	12
BREAST	Post-Golgi vesicle-mediated transport →	+0.071	+0.747	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,536 associations by consensus.

Cytosolic transport by RNF115 expression — OVARY

Explore this box plot interactively →