RNF112

Across TCGA cell cohorts, RNF112 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,191 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RNF112-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of autophagy, and Embryonic brain development. Each is linked with RNF112 in more than 11 cancer types. Because this analysis shows association rather than direction, both RNF112-to-partner and partner-to-RNF112 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by RNF112-low versus RNF112-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF112→partner) and Y-score (partner→RNF112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.147	+1.567	<.001	<.001	3	12
OESOPHAGUS	Negative regulation of autophagy →	+0.078	+1.404	<.001	.001	3	11
OESOPHAGUS	Embryonic brain development →	-0.140	-1.917	<.001	<.001	3	11
OESOPHAGUS	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.073	+1.620	.001	<.001	3	11
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.150	+1.509	<.001	.001	3	11
OESOPHAGUS	Regulation of proteasomal protein catabolic process →	+0.080	+1.500	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,191 associations by consensus.

Negative regulation of myoblast fusion by RNF112 expression — OESOPHAGUS

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