RNF112

Across TCGA cell cohorts, RNF112 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RNF112-associated genes across cancer lineages are KRTAP10-3, GAGE12C, and USP29. Each is linked with RNF112 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF112-to-partner and partner-to-RNF112 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-3 grouped by RNF112-low versus RNF112-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF112→partner) and Y-score (partner→RNF112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KRTAP10-3 →	+0.032	+5.228	<.001	.005	3	2
LUNG_NSCLC_LUAD	GAGE12C →	+1.371	+5.228	.001	.005	3	2
LUNG_NSCLC_LUAD	USP29 →	+0.016	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	RNASE9 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	GAGE12D →	+2.651	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	CXorf51B →	+1.088	+5.228	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

KRTAP10-3 by RNF112 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →