RNF103

Across TCGA cell cohorts, RNF103 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,386 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF103-associated GO terms across cancer lineages are Golgi vesicle transport, Endoplasmic reticulum mannose trimming, and Macroautophagy. Each is linked with RNF103 in more than 16 cancer types. Because this analysis shows association rather than direction, both RNF103-to-partner and partner-to-RNF103 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by RNF103-low versus RNF103-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF103→partner) and Y-score (partner→RNF103) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.063	+0.833	.003	<.001	3	17
BONE	Endoplasmic reticulum mannose trimming →	+0.113	+0.896	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.055	+0.585	.004	.004	3	15
OVARY	ERAD pathway →	+0.085	+0.708	<.001	.002	2	16
URINARY_TRACT	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.071	+0.830	<.001	<.001	3	15
PANCREAS	Vesicle budding from membrane →	+0.064	+0.948	.003	<.001	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,386 associations by consensus.

Golgi vesicle transport by RNF103 expression — UPPER_AERODIGESTIVE_TRACT

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