RNF103

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RNF103 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RNF103-associated genes across cancer lineages are NOBOX, RPL10L, and OR13C7. Each is linked with RNF103 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF103-to-partner and partner-to-RNF103 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOBOX grouped by RNF103-low versus RNF103-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF103→partner) and Y-score (partner→RNF103) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaNOBOX →+0.002+3.925<.001.00632
BLOOD_LymphomaRPL10L →+0.106+3.021<.001.00632
BLOOD_LeukemiaOR13C7 →+0.011+3.969<.001.00932
BLOOD_LymphomaKLHL40 →+0.007+3.794<.001.00131
BLOOD_LymphomaDPPA2 →+0.197+3.353<.001.00231
BLOOD_LymphomaGBX1 →+0.272+3.165<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

NOBOX by RNF103 expression — BLOOD_Lymphoma

Box plot of NOBOX in RNF103-low vs RNF103-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration