RND1

Across TCGA cell cohorts, RND1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,056 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RND1-associated GO terms across cancer lineages are Regulation of endoplasmic reticulum unfolded protein response, Proteasomal ubiquitin-independent protein catabolic process, and Diapedesis. Each is linked with RND1 in more than 9 cancer types. Because this analysis shows association rather than direction, both RND1-to-partner and partner-to-RND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of endoplasmic reticulum unfolded protein response grouped by RND1-low versus RND1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RND1→partner) and Y-score (partner→RND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of endoplasmic reticulum unfolded protein response →	+0.107	+1.488	<.001	<.001	3	10
LUNG_SCLC	Proteasomal ubiquitin-independent protein catabolic process →	+0.105	+0.965	<.001	.009	2	10
BONE	Diapedesis →	-0.961	-0.883	.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.120	+1.752	<.001	<.001	3	8
LIVER	Retrograde protein transport, ER to cytosol →	+0.117	+3.020	.002	<.001	3	8
LIVER	Protein exit from endoplasmic reticulum →	+0.100	+2.202	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,056 associations by consensus.

Regulation of endoplasmic reticulum unfolded protein response by RND1 expression — PANCREAS

Explore this box plot interactively →