RND1

Across TCGA pan-cancer cohorts, RND1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of RND1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RND1 RNA is repressed in tumor relative to normal tissue. In most cancer types RND1 is over-expressed in tumor, although a few such as HNSC and KICH show the opposite, repressed pattern.

HNSC, KICH, and BLCA are the cancer types where RND1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RND1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	−0.953	<.001	10	view →
KICH	All	III,IV	−2.162	.001	9	view →
BLCA	All	All	−1.357	.001	8	view →
LUSC	Male	II,III,IV	−4.076	<.001	6	view →
BRCA	All	III,IV	+1.539	<.001	6	view →
KIRC	All	All	+0.514	<.001	6	view →
LUAD	All	All	−0.846	.006	2	view →
THCA	All	All	−0.553	.005	2	view →
ESCA	All	All	+1.340	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

RND1–HNSC

Open the HNSC breakdown →