RNASEL

Across TCGA patient cohorts, RNASEL protein abundance is significantly associated with the RNA expression of many other genes, with 12,502 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RNASEL-associated genes across cancer lineages are MR1, KIAA0040, and CTSO. Each is linked with RNASEL in more than 5 cancer types. Because this analysis shows association rather than direction, both RNASEL-to-partner and partner-to-RNASEL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNASEL versus MR1 in LSCC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASEL→partner) and Y-score (partner→RNASEL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MR1 →	+0.809	+0.427	<.001	<.001	3	6
BRCA	KIAA0040 →	+1.350	+0.435	<.001	<.001	3	6
UCEC	CTSO →	+0.654	+0.398	<.001	<.001	3	6
UCEC	CPQ →	+1.006	+0.381	<.001	<.001	3	5
UCEC	CPED1 →	+0.836	+0.326	<.001	<.001	3	5
OV	HFE →	+0.826	+0.379	.003	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,502 associations by consensus.

RNASEL vs MR1 — LSCC

Explore this scatter interactively →