RNASEH2C

Across TCGA patient cohorts, RNASEH2C RNA expression is significantly associated with the protein abundance of many other proteins, with 11,468 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNASEH2C-associated proteins across cancer lineages are PMM2, RNASEH2A, and HM13. Each is linked with RNASEH2C in more than 4 cancer types. Because this analysis shows association rather than direction, both RNASEH2C-to-partner and partner-to-RNASEH2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNASEH2C versus PMM2 in BRCA, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASEH2C→partner) and Y-score (partner→RNASEH2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PMM2 →	-0.381	-0.591	.001	<.001	3	5
UCEC	RNASEH2A →	+0.422	+0.780	<.001	<.001	3	4
UCEC	HM13 →	-0.611	-0.739	.001	<.001	3	4
LSCC	UBXN7 →	+0.331	+0.241	.004	.004	3	4
GBM	P4HB →	-0.359	-0.223	<.001	.001	3	4
GBM	SPIN1 →	+0.357	+0.288	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,468 associations by consensus.

RNASEH2C vs PMM2 — BRCA

Explore this scatter interactively →