RNASEH2B

Across TCGA patient cohorts, RNASEH2B protein abundance is significantly associated with the RNA expression of many other genes, with 12,146 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RNASEH2B-associated genes across cancer lineages are RFC3, NUFIP1, and BRCA2. Each is linked with RNASEH2B in more than 6 cancer types. Because this analysis shows association rather than direction, both RNASEH2B-to-partner and partner-to-RNASEH2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNASEH2B versus RFC3 in UCEC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASEH2B→partner) and Y-score (partner→RNASEH2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RFC3 →	+1.149	+0.555	<.001	<.001	3	7
LSCC	NUFIP1 →	+0.664	+0.412	<.001	<.001	3	7
UCEC	BRCA2 →	+1.224	+0.486	<.001	<.001	3	7
UCEC	DIAPH3 →	+1.397	+0.585	<.001	<.001	3	7
LSCC	CENPJ →	+0.732	+0.505	<.001	<.001	3	7
LSCC	MRPS31 →	+0.502	+0.448	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,146 associations by consensus.

RNASEH2B vs RFC3 — UCEC

Explore this scatter interactively →