RNASEH1P2

Across TCGA patient cohorts, RNASEH1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,674 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNASEH1P2-associated GO terms across cancer lineages are Telomere maintenance, rRNA metabolic process, and Telomere organization. Each is linked with RNASEH1P2 in more than 18 cancer types. Because this analysis shows association rather than direction, both RNASEH1P2-to-partner and partner-to-RNASEH1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance grouped by RNASEH1P2-low versus RNASEH1P2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASEH1P2→partner) and Y-score (partner→RNASEH1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telomere maintenance →	+0.064	+0.286	<.001	<.001	3	19
STAD	rRNA metabolic process →	+0.070	+0.317	<.001	<.001	3	18
ESCA	Telomere organization →	+0.067	+0.273	.003	<.001	3	17
STAD	Negative regulation of DNA repair →	+0.053	+0.271	<.001	<.001	3	17
STAD	Negative regulation of DNA metabolic process →	+0.055	+0.274	<.001	<.001	3	17
STAD	tRNA modification →	+0.054	+0.270	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,674 associations by consensus.

Telomere maintenance by RNASEH1P2 expression — STAD

Explore this box plot interactively →