RNASEH1P2

Across TCGA pan-cancer cohorts, RNASEH1P2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNASEH1P2’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RNASEH1P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNASEH1P2 is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

BLCA, COAD, and HNSC are the cancer types where RNASEH1P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNASEH1P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.102	.016	5	view →
COAD	All	All	+0.101	.012	2	view →
HNSC	All	All	+0.037	.027	2	view →
ESCA	Female	All	−0.170	.045	1	view →
LUAD	All	All	+0.037	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RNASEH1P2–BLCA

Open the BLCA breakdown →