RNASEH1-AS1

Across TCGA pan-cancer cohorts, RNASEH1-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNASEH1-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNASEH1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNASEH1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and OV show a favorable association.

ACC, UCS, and MESO are the cancer types where RNASEH1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.253	0.674	<.001	117	view →
UCS	DFS	Median	II,III,IV	0.509	0.210	.003	52	view →
MESO	DFS	Tertile	IV	0.148	0.561	.001	50	view →
LIHC	OS	Quartile	All	0.579	0.776	.001	39	view →
LUAD	OS	Quartile	All	0.645	0.778	.005	31	view →
CESC	DFS	Median	IV	0.307	0.686	.006	28	view →
OV	OS	Median	All	0.883	0.797	.003	26	view →
LAML	DFS	Tertile	All	0.242	0.505	.008	24	view →
BLCA	OS	Quartile	IV	0.154	0.380	.012	20	view →
UVM	DFS	Quartile	All	0.321	1.000	.017	19	view →
KIRC	DFS	Tertile	All	0.722	0.489	.007	18	view →
LGG	OS	Tertile	All	0.839	0.931	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RNASEH1-AS1–ACC (DFS)

Open the ACC breakdown →