RNASE12

Across TCGA patient cohorts, RNASE12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,792 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNASE12-associated GO terms across cancer lineages are Organic acid catabolic process, Peptidyl-proline modification, and Lipid oxidation. Each is linked with RNASE12 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNASE12-to-partner and partner-to-RNASE12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organic acid catabolic process grouped by RNASE12-low versus RNASE12-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE12→partner) and Y-score (partner→RNASE12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Organic acid catabolic process →	+0.123	+0.019	<.001	<.001	3	4
STAD	Peptidyl-proline modification →	+0.173	+0.018	<.001	<.001	3	3
STAD	Lipid oxidation →	+0.127	+0.015	<.001	.004	3	3
STAD	Fatty acid derivative metabolic process →	+0.115	+0.023	<.001	<.001	3	3
STAD	Alpha-amino acid metabolic process →	+0.111	+0.018	<.001	<.001	3	3
STAD	Nucleoside bisphosphate metabolic process →	+0.135	+0.019	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,792 associations by consensus.

Organic acid catabolic process by RNASE12 expression — STAD

Explore this box plot interactively →