RNASE12

Across TCGA cell cohorts, RNASE12 RNA expression is significantly associated with the mutation status of many other genes, with 2 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible RNASE12-associated genes across cancer lineages are ABCC11 and GAPVD1. Each is linked with RNASE12 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNASE12-to-partner and partner-to-RNASE12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABCC11 grouped by RNASE12-low versus RNASE12-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE12→partner) and Y-score (partner→RNASE12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ABCC11 →	+4.614	+0.025	.004	<.001	3	1
PANCREAS	GAPVD1 →	+5.614	+0.033	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ABCC11 by RNASE12 expression — PANCREAS

Explore this box plot interactively →