RNASE11

Across TCGA patient cohorts, RNASE11 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,879 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNASE11-associated GO terms across cancer lineages are Positive regulation of immune effector process, Glucan metabolic process, and Regulation of glycogen biosynthetic process. Each is linked with RNASE11 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNASE11-to-partner and partner-to-RNASE11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of immune effector process grouped by RNASE11-low versus RNASE11-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE11→partner) and Y-score (partner→RNASE11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of immune effector process →	+0.084	+0.011	<.001	<.001	3	4
STAD	Glucan metabolic process →	+0.099	+0.012	<.001	<.001	3	4
STAD	Regulation of glycogen biosynthetic process →	+0.106	+0.012	<.001	<.001	3	4
STAD	Protein targeting to lysosome →	+0.130	+0.011	<.001	<.001	3	4
STAD	Hyperosmotic response →	+0.120	+0.010	<.001	<.001	3	4
STAD	Regulation of early endosome to late endosome transport →	+0.136	+0.015	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,879 associations by consensus.

Positive regulation of immune effector process by RNASE11 expression — STAD

Explore this box plot interactively →