RNASE11

Across TCGA cell cohorts, RNASE11 mutation is significantly associated with the drug of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNASE11-associated genes across cancer lineages are 50869, Quizartinib, and GSK2110183B. Each is linked with RNASE11 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNASE11-to-partner and partner-to-RNASE11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 50869 grouped by RNASE11-low versus RNASE11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE11→partner) and Y-score (partner→RNASE11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	50869 →	+0.505	+2.871	.010	.021	3	1
LARGE_INTESTINE	Quizartinib →	+0.378	+2.874	.012	.021	3	1
LARGE_INTESTINE	GSK2110183B →	+0.589	+2.871	.041	.021	2	1
LARGE_INTESTINE	Docetaxel →	+0.951	+2.807	.046	.045	2	1
LARGE_INTESTINE	P22077 →	+0.485	+2.871	.025	.021	2	1
LARGE_INTESTINE	Lenalidomide →	+0.286	+2.807	.037	.046	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

50869 by RNASE11 expression — LARGE_INTESTINE

Explore this box plot interactively →