RNA5SP464

Across TCGA pan-cancer cohorts, RNA5SP464 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP464’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where RNA5SP464 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP464 is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.

ESCA, LIHC, and LUAD are the cancer types where RNA5SP464 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP464 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	+1.214	.041	2	view →
LIHC	All	All	+0.075	.024	2	view →
LUAD	Male	III,IV	−0.446	.049	1	view →
LUSC	Female	II,III,IV	+0.365	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNA5SP464–ESCA

Open the ESCA breakdown →