Across TCGA pan-cancer cohorts, RNA5SP450 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNA5SP450 data layer.
The strongest signal is observed in uveal melanoma (UVM), where higher RNA5SP450 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNA5SP450 expression acts as an unfavorable survival marker, although some lineages such as UCS and TGCT show a favorable association.
UVM, LUSC, and ACC are the cancer types where RNA5SP450 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.