RNA5SP440

Across TCGA patient cohorts, RNA5SP440 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,325 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible RNA5SP440-associated GO terms across cancer lineages are tRNA metabolic process, Macromolecule methylation, and Regulation of telomere maintenance. Each is linked with RNA5SP440 in more than 15 cancer types. Because this analysis shows association rather than direction, both RNA5SP440-to-partner and partner-to-RNA5SP440 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA metabolic process grouped by RNA5SP440-low versus RNA5SP440-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP440→partner) and Y-score (partner→RNA5SP440) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	tRNA metabolic process →	+0.052	+0.418	.004	.001	3	16
DLBC	Macromolecule methylation →	+0.058	+0.491	.001	<.001	2	16
DLBC	Regulation of telomere maintenance →	+0.073	+0.256	<.001	.003	3	14
DLBC	Positive regulation of DNA metabolic process →	+0.069	+0.372	<.001	.005	2	15
DLBC	P-body assembly →	+0.084	+0.459	<.001	<.001	3	14
DLBC	Amino acid activation →	+0.052	+0.241	.004	.004	1	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,325 associations by consensus.

tRNA metabolic process by RNA5SP440 expression — ESCA

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