Q-omics provides the consensus-scored RNA5SP37 profile across patient tissues and cancer cell-line models. RNA5SP37 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, RNA5SP37 is differentially expressed in 6, with the highest sampling consensus in COAD. Additionally, RNA5SP37 RNA expression shows 16,700 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight THCA, COAD, and THYM as cancer lineages where RNA5SP37 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNA5SP37 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNA5SP37 survival associations across molecular data types. RNA5SP37 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNA5SP37 RNA expression–survival associations across cancer types. High RNA5SP37 expression shows unfavorable associations in THCA, LUSC and THYM, but favorable associations in READ, UVM and BRCA. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify THCA as the clearest survival context for RNA5SP37 RNA expression.
This table summarizes RNA5SP37 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for RNA5SP37. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNA5SP37 shows lower tumor expression in BRCA, THCA, KICH and KIRP and higher tumor expression in COAD and STAD. The COAD box plot shows higher RNA5SP37 RNA expression in tumor versus normal tissue (log2 FC = +0.573, t-test p = .001).
This table shows molecular features associated with RNA5SP37 in patient tissues and cancer cell lines. In patient samples, RNA5SP37 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
