RNA5SP339

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNA5SP339 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNA5SP339 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RNA5SP339 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNA5SP339 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LGG show a favorable association.

LUSC, LIHC, and STAD are the cancer types where RNA5SP339 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCDFSTertileAll0.1770.723<.00187view →
LIHCDFSTertileII,III,IV0.0670.417<.00133view →
STADDFSTertileIV0.1350.474.01227view →
KIRPOSTertileAll0.2530.718<.00121view →
ACCDFSTertileII,III,IV0.2420.724.03418view →
MESODFSTertileAll0.0980.366.03918view →
HNSCDFSTertileIII,IV0.4370.668.02218view →
CHOLOSTertileIII,IV0.2750.886.04518view →
KIRCDFSTertileIII,IV0.7940.618.02418view →
LGGOSTertileAll0.9690.886.0306view →
KICHDFSTertileAll0.4600.878.0143view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

Exploration