Across TCGA pan-cancer cohorts, RNA5SP339 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP339’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where RNA5SP339 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP339 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.
STAD, BRCA, and THCA are the cancer types where RNA5SP339 tumor–normal differential expression is most reproducible.