Q-omics provides the consensus-scored RN7SL253P profile across patient tissues and cancer cell-line models. RN7SL253P expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in CHOL. Among the 18 cancer types available for tumor–normal comparison, RN7SL253P is differentially expressed in 5, with the highest sampling consensus in THCA. Additionally, RN7SL253P RNA expression shows 6,754 significant gene co-expression associations, with the highest sampling consensus in LAML. Together, these results highlight CHOL, THCA, and LAML as cancer lineages where RN7SL253P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RN7SL253P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RN7SL253P survival associations across molecular data types. RN7SL253P RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RN7SL253P RNA expression–survival associations across cancer types. High RN7SL253P expression shows unfavorable associations in CHOL, OV, ESCA, ACC and MESO, but favorable associations in THCA. The CHOL Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify CHOL as the clearest survival context for RN7SL253P RNA expression.
This table summarizes RN7SL253P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for RN7SL253P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RN7SL253P shows lower tumor expression in LUSC and COAD and higher tumor expression in THCA, PRAD and LUAD. The THCA box plot shows higher RN7SL253P RNA expression in tumor versus normal tissue (log2 FC = +0.196, t-test p < 0.001).
This table shows molecular features associated with RN7SL253P in patient tissues and cancer cell lines. In patient samples, RN7SL253P shows the broadest associations at the RNA and protein expression levels, with LAML recurring as the lineage with the largest associated feature set.
