RN7SL250P

Across TCGA pan-cancer cohorts, RN7SL250P RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RN7SL250P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RN7SL250P RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SL250P is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, UCEC, and LUAD are the cancer types where RN7SL250P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RN7SL250P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	All	−0.298	<.001	9	view →
UCEC	All	All	+1.261	<.001	6	view →
LUAD	All	All	−0.177	<.001	6	view →
KICH	All	All	−0.208	<.001	5	view →
BRCA	All	All	−0.101	<.001	4	view →
KIRP	All	All	−0.074	.005	2	view →
COAD	All	II,III,IV	−0.042	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RN7SL250P–LUSC

Open the LUSC breakdown →