RN7SL248P

Across TCGA patient cohorts, RN7SL248P mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RN7SL248P-associated genes across cancer lineages are eIF4E, Fibronectin, and MEK1. Each is linked with RN7SL248P in more than 1 cancer types. Because this analysis shows association rather than direction, both RN7SL248P-to-partner and partner-to-RN7SL248P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by RN7SL248P-low versus RN7SL248P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RN7SL248P→partner) and Y-score (partner→RN7SL248P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.207	+3.584	.014	.002	3	1
UCEC	Fibronectin →	-0.272	-2.308	.040	.033	3	1
UCEC	MEK1 →	+0.413	+3.459	.004	.005	3	1
UCEC	Myosin-IIa_pS1943 →	+0.216	+2.000	.009	.030	3	1
UCEC	Myosin-IIa →	+0.189	+3.332	.019	.005	3	1
UCEC	p62 Lck ligand →	+0.333	+3.179	.011	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

eIF4E by RN7SL248P expression — UCEC

Explore this box plot interactively →