Across TCGA pan-cancer cohorts, RN7SKP259 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RN7SKP259’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RN7SKP259 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SKP259 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, KIRC, and BRCA are the cancer types where RN7SKP259 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RN7SKP259 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.086	.005	5	view →
KIRC	All	II,III,IV	+0.039	.024	5	view →
BRCA	Female	All	+0.103	.002	4	view →
THCA	All	All	−0.059	.005	4	view →
LIHC	All	All	+0.074	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RN7SKP259 RNA expression & survival · all RN7SKP259 data types