Across TCGA pan-cancer cohorts, RN7SKP163 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RN7SKP163’s most consistent transcriptional readouts.
The strongest signal is observed in rectum adenocarcinoma (READ), where RN7SKP163 RNA is repressed in tumor relative to normal tissue. In most cancer types RN7SKP163 is over-expressed in tumor, although a few such as READ and BRCA show the opposite, repressed pattern.
READ, BRCA, and BRCA are the cancer types where RN7SKP163 tumor–normal differential expression is most reproducible.