RMND5B

Across TCGA cell cohorts, RMND5B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,540 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RMND5B-associated GO terms across cancer lineages are mRNA alternative polyadenylation, Negative regulation of autophagosome maturation, and Regulation of protein localization to centrosome. Each is linked with RMND5B in more than 13 cancer types. Because this analysis shows association rather than direction, both RMND5B-to-partner and partner-to-RMND5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by RMND5B-low versus RMND5B-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RMND5B→partner) and Y-score (partner→RMND5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	mRNA alternative polyadenylation →	+0.076	+0.671	<.001	<.001	3	14
PANCREAS	Negative regulation of autophagosome maturation →	+0.100	+0.802	<.001	<.001	3	13
BONE	Regulation of protein localization to centrosome →	+0.111	+0.602	<.001	.004	3	13
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.177	+0.547	.001	.006	3	13
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven ATP synthesis →	+0.094	+0.806	.001	.002	3	13
BONE	Transcription pausing by RNA polymerase II →	+0.147	+0.548	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,540 associations by consensus.

mRNA alternative polyadenylation by RMND5B expression — LARGE_INTESTINE

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