RMND5A

Across TCGA pan-cancer cohorts, RMND5A mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RMND5A data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RMND5A mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RMND5A expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC, LUAD, and CCRCC are the cancer types where RMND5A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	1.000	0.881	.015	10	view →
LUAD	OS	Median	III,IV	0.413	0.791	.034	5	view →
CCRCC	OS	Quartile	II,III,IV	0.819	1.000	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RMND5A–LSCC (OS)

Open the LSCC breakdown →