RMND5A

Across TCGA pan-cancer cohorts, RMND5A RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of RMND5A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RMND5A RNA is repressed in tumor relative to normal tissue. In most cancer types RMND5A is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, LUSC, and KIRC are the cancer types where RMND5A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RMND5A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−1.217	<.001	8	view →
LUSC	Female	All	+0.880	<.001	7	view →
KIRC	Male	II,III,IV	−0.322	.011	5	view →
COAD	Female	All	−0.641	.001	4	view →
LUAD	Female	II,III,IV	−0.583	.001	4	view →
BLCA	All	All	+0.417	.018	4	view →
KIRP	Male	All	−0.635	<.001	2	view →
LIHC	All	All	+0.304	.031	2	view →
PRAD	All	All	+0.209	.038	2	view →
ESCA	Female	All	+1.313	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

RMND5A–KICH

Open the KICH breakdown →