RMND5A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RMND5A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RMND5A-associated genes across cancer lineages are OR1M1 and OR10G7. Each is linked with RMND5A in more than 1 cancer types. Because this analysis shows association rather than direction, both RMND5A-to-partner and partner-to-RMND5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1M1 grouped by RMND5A-low versus RMND5A-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMND5A→partner) and Y-score (partner→RMND5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCOR1M1 →+0.016+5.643<.001.00231
LUNG_SCLCOR10G7 →+0.033+5.029<.001.00631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR1M1 by RMND5A expression — LUNG_SCLC

Box plot of OR1M1 in RMND5A-low vs RMND5A-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration