RMND1

Across TCGA cell cohorts, RMND1 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible RMND1-associated genes across cancer lineages are PRSS58, SSMEM1, and TFDP3. Each is linked with RMND1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RMND1-to-partner and partner-to-RMND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS58 grouped by RMND1-low versus RMND1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMND1→partner) and Y-score (partner→RMND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PRSS58 →	+0.092	+5.000	<.001	.006	3	1
LARGE_INTESTINE	SSMEM1 →	+0.023	+3.707	.008	.009	3	1
LARGE_INTESTINE	TFDP3 →	+0.024	+4.196	<.001	.002	3	1
LARGE_INTESTINE	C14orf180 →	+0.124	+4.155	<.001	.003	3	1
UPPER_AERODIGESTIVE_TRACT	RFPL3 →	+0.062	+3.632	.002	.009	3	1
UPPER_AERODIGESTIVE_TRACT	ENAM →	+0.057	+3.917	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

PRSS58 by RMND1 expression — PANCREAS

Explore this box plot interactively →