RMI2

Across TCGA patient cohorts, RMI2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RMI2-associated genes across cancer lineages are MIR4692, TRAV7, and RPSAP64. Each is linked with RMI2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RMI2-to-partner and partner-to-RMI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4692 grouped by RMI2-low versus RMI2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMI2→partner) and Y-score (partner→RMI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4692 →	+0.854	+5.453	<.001	<.001	3	1
UCEC	TRAV7 →	+0.320	+3.638	<.001	.006	3	1
UCEC	RPSAP64 →	+0.435	+3.914	<.001	.002	3	1
UCEC	LINC01214 →	+0.420	+3.239	<.001	.009	3	1
UCEC	LINC01340 →	+0.197	+3.454	<.001	.006	3	1
UCEC	RNA5SP20 →	+0.622	+3.982	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MIR4692 by RMI2 expression — UCEC

Explore this box plot interactively →