RMDN2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RMDN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,614 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RMDN2-associated GO terms across cancer lineages are Proteasomal ubiquitin-independent protein catabolic process, Negative regulation of syncytium formation by plasma membrane fusion, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with RMDN2 in more than 8 cancer types. Because this analysis shows association rather than direction, both RMDN2-to-partner and partner-to-RMDN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasomal ubiquitin-independent protein catabolic process grouped by RMDN2-low versus RMDN2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RMDN2→partner) and Y-score (partner→RMDN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYProteasomal ubiquitin-independent protein catabolic process →+0.090+1.053<.001<.00138
OVARYNegative regulation of syncytium formation by plasma membrane fusion →+0.103+0.944<.001.00338
BREASTMitochondrial electron transport, cytochrome c to oxygen →+0.069+0.934.001<.00129
PANCREASProtein localization to vacuole →+0.069+0.939<.001<.00137
OVARYAerobic respiration →+0.077+0.898.001.00337
LUNG_SCLCVesicle fusion with Golgi apparatus →+0.101+1.029.002.00237
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,614 associations by consensus.

Proteasomal ubiquitin-independent protein catabolic process by RMDN2 expression — OVARY

Box plot of Proteasomal ubiquitin-independent protein catabolic process in RMDN2-low vs RMDN2-high samples in OVARY.

Explore this box plot interactively →

Exploration