RMDN2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RMDN2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RMDN2-associated genes across cancer lineages are OR5P3 and C9orf92. Each is linked with RMDN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RMDN2-to-partner and partner-to-RMDN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5P3 grouped by RMDN2-low versus RMDN2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMDN2→partner) and Y-score (partner→RMDN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR5P3 →+0.108+5.201<.001.00631
BLOOD_LeukemiaC9orf92 →+0.109+5.539<.001.00331
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR5P3 by RMDN2 expression — BLOOD_Leukemia

Box plot of OR5P3 in RMDN2-low vs RMDN2-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration