RLN1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RLN1 protein abundance is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RLN1-associated genes across cancer lineages are POLR2C, TCHH, and ZCCHC12. Each is linked with RLN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RLN1-to-partner and partner-to-RLN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RLN1 versus POLR2C in UCEC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RLN1→partner) and Y-score (partner→RLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPOLR2C →-0.609-0.359.005<.00121
UCECTCHH →+0.150+0.399.008.00421
UCECZCCHC12 →-1.225-0.359<.001<.00121
UCECRNU6-414P →+1.029+0.359.007<.00121
UCECRNU6-1105P →-1.200-0.359<.001<.00121
UCECMIRLET7F2 →-1.755-0.359<.001<.00121
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

RLN1 vs POLR2C — UCEC

Per-sample scatter of RLN1 vs POLR2C in UCEC (Pearson r = -0.41).

Explore this scatter interactively →

Exploration