RLN1

Across TCGA patient cohorts, RLN1 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RLN1-associated genes across cancer lineages are SIGLEC27P, RNA5SP231, and LINC02647. Each is linked with RLN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RLN1-to-partner and partner-to-RLN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIGLEC27P grouped by RLN1-low versus RLN1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RLN1→partner) and Y-score (partner→RLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SIGLEC27P →	+0.105	+6.392	<.001	.001	3	2
BLCA	RNA5SP231 →	+0.893	+7.640	<.001	.009	3	2
BLCA	LINC02647 →	+0.294	+7.640	<.001	.009	3	2
SKCM	RNU6-1127P →	+0.419	+5.867	<.001	.003	3	2
BLCA	RNU6-832P →	+0.353	+7.640	<.001	.009	3	1
BLCA	RNU6-639P →	+0.588	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

SIGLEC27P by RLN1 expression — COAD

Explore this box plot interactively →