RIT1

Across TCGA patient cohorts, RIT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,314 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RIT1-associated proteins across cancer lineages are HDGF, ANP32E, and TIPRL. Each is linked with RIT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RIT1-to-partner and partner-to-RIT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIT1 versus HDGF in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RIT1→partner) and Y-score (partner→RIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HDGF →	+0.356	+0.296	<.001	<.001	3	7
LUAD	ANP32E →	+0.530	+0.480	<.001	<.001	3	7
UCEC	TIPRL →	+0.223	+0.422	<.001	<.001	3	6
LSCC	PRCC →	+0.283	+1.013	<.001	<.001	3	6
LSCC	GATAD2B →	+0.248	+0.673	<.001	<.001	3	6
HNSC	RPRD2 →	+0.364	+0.713	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,314 associations by consensus.

RIT1 vs HDGF — GBM

Explore this scatter interactively →